BACKGROUND:RA patients being treated Serving Pitchers with biologics are known to have an increased risk of infections.We recently demonstrated that both CTLA4 Ig and anti-TNF treatment aggravate systemic Staphylococcus aureus (S.aureus) infection in mice, but with distinct clinical manifestations.However, the effects of CTLA4 Ig and anti-TNF treat
Hardware Salvage in the Lower Extremity after Flap Coverage: 10-Year Single Center Outcomes Analysis
Background:.An unanswered question with open tibial fractures is whether the type of flap used affects hardware retention.Flap survival may not equate hardware retention or limb salvage.In Serving Pitchers this study, we performed a 10-year single institution review and analysis of all patients who had placement of hardware for open tibial fracture
Opportunities and Challenges in the Delivery of mRNA-Based Vaccines
In the past few years, there Baselayer has been increasing focus on the use of messenger RNA (mRNA) as a new therapeutic modality.Current clinical efforts encompassing mRNA-based drugs are directed toward infectious disease vaccines, cancer immunotherapies, therapeutic protein replacement therapies, and treatment of genetic diseases.However, challe